Andrew Krystal, MD
Sleep Medicine, Mood, and Anxiety Spectrum Disorders
Andrew Krystal, MD is a Board-Certified Clinical Neurophysiology and an industry-renowned expert on sleep and mood disorders, with more than 25 years of experience in patient care and research settings. After graduating from Massachusetts Institute with a master’s in Biomechanical Engineering, Dr. Krystal continued his education at Duke University where he successfully earned his medical degree and then completed a residency in psychiatry at Duke, followed by fellowships in sleep medicine and clinical neurophysiology (studying the nervous system through recording the body’s electrical activity).
Dr. Krystal is regarded as a psychiatrist who cares for adults with mood and anxiety spectrum disorders as well as all types of sleep disorders including insomnia. His research efforts focus on understanding insomnia’s causes and how insomnia may be related to psychiatric or other medical conditions. He is passionate about finding new treatments for sleep disorders and investigates how sleep maintains and restores normal human functions. Pioneering the application of computational modeling to the study of biomarker development using EEG in patients with depression and sleep disorders, Dr. Krystal uses these applications of biomarkers in treatment development clinical trials. He has been the principal investigator of more than 50 single-site and multi-site clinical trials.
Dr. Krystal is the president of the Sleep Research Society and a member of the American Academy of Sleep Medicine, American Psychiatric Association, and American College of Neuropsychopharmacology. He serves on the examination committee of the American Board of Sleep Medicine, which allows medical professionals to pursue certification in sleep medicine. Dr. Krystal has held various leadership positions and served as a faculty member and physician at Duke Health for more than two decades before joining UCSF in 2016. Currently, Dr. Krystal is the Director, Clinical and Translational Sleep Research Program Director, Mood and Anxiety Spectrum Disorders and Interventional Psychiatry Programs Ray and Dagmar Dolby Distinguished Professor Vice Chair for Research in Psychiatry.