The International Society for CNS Clinical Trials and Methodology (ISCTM) is an independent multi-disciplinary organization devoted to promoting advances in, and dissemination of, clinical research methods related to development and use of CNS therapeutics. The ISCTM accomplishes this by bringing together international stakeholders representing academia, industry, government, payers, policymakers, and the public to address strategic clinical, regulatory, methodological and policy challenges in clinical research.